AGE 6+

FOR MILD TO MODERATE
ECZEMA (ATOPIC DERMATITIS)

RESULTS

Rapid and reliable relief in a steroid-free cream

Symptoms illustrated.
Not an actual patient.

ZORYVE was evaluated as a once-daily, steroid-free, stand-alone treatment over the course of 4 weeks in 2 clinical trials of 1,337 people aged 6 and older with mild to moderate eczema. 884 people used ZORYVE daily for 4 weeks. 453 people used the same cream without the active ingredient (the inactive cream) daily for 4 weeks.

Clear or Almost Clear skin*

31% of people using ZORYVE had Clear or Almost Clear skin* in 4 weeks vs 14% of people using inactive cream

ZORYVE atopic dermatitis treatment efficacy chart31%ZORYVECream14%InactiveCream
ZORYVE atopic dermatitis treatment efficacy chart31%ZORYVECream14%InactiveCream
ZORYVE atopic dermatitis treatment efficacy chart31%ZORYVECream14%InactiveCream
92%92% of 816 people had disease improvement with ZORYVE in 4 weeks vs 77% of 419 people using inactive cream
92% of 816 people had disease improvement with ZORYVE in 4 weeks vs 77% of 419 people using inactive cream 92%

*People who had Clear or Almost Clear skin and a 2-point improvement on a 5-point severity scale. 0 = Clear, 1 = Almost Clear, 2 = Mild, 3 = Moderate, 4 = Severe.

Fast itch relief

32% of 542 people using ZORYVE had significant itch relief in 4 weeks vs 17% of 271 people using inactive cream

ZORYVE atopic dermatitis clinical study itch results17%InactiveCream32%ZORYVECream
ZORYVE atopic dermatitis clinical study itch results17%InactiveCream32%ZORYVECream

Symptoms illustrated. Not an actual patient.

People using ZORYVE felt greater itch relief 24 hours after first application compared to people using inactive cream

Most common side effects

ZORYVE atopic dermatitis treatment most common side effects tableVomiting1.5%HeadacheNausea2.9%1.9%Application site pain1.5%Diarrhea1.5%SIDE EFFECTSZORYVE885 people451 people0.9%0.4%0.7%0.4%0.4%INACTIVE CREAM
ZORYVE atopic dermatitis treatment most common side effects tableSIDE EFFECTSHeadacheNauseaApplication site painDiarrheaVomiting2.9%1.9%1.5%1.5%1.5%0.9%0.4%0.7%0.4%0.4%ZORYVE885 people451 peopleINACTIVE CREAM
ZORYVE atopic dermatitis treatment most common side effects tableSIDE EFFECTSHeadacheNauseaApplication site painDiarrheaVomiting2.9%1.9%1.5%1.5%1.5%1.5%1.5%0.9%0.4%0.7%0.4%0.4%0.4%ZORYVE885 people451 peopleINACTIVE CREAM

These are not all the possible side effects of ZORYVE cream. Call your doctor for medical advice about side effects.

Low rates of stinging or burning (1.6%) were reported after first application of ZORYVE vs 2.0% with inactive cream

Results you can see and feel anywhere on the skin

Actual clinical trial patients.

Inside Elbow

12-YEAR-OLD

Day 0
Inside elbow of clinical trial patient before starting treatment with ZORYVE
Inside elbow of clinical trial patient 1 week after ZORYVE treatment
Inside elbow of clinical trial patient 4 weeks after ZORYVE treatment

Face

9-YEAR-OLD

Day 0
Face of clinical trial patient before starting treatment with ZORYVE
Face of clinical trial patient 1 week after ZORYVE treatment
Face of clinical trial patient 4 weeks after ZORYVE treatment

Ankle

65-YEAR-OLD

Day 0
Ankle of clinical trial patient before starting treatment with ZORYVE
Ankle of clinical trial patient 1 week after ZORYVE treatment
Ankle of clinical trial patient 4 weeks after ZORYVE treatment

Hand & Inside Wrist

24-YEAR-OLD

Day 0
Hand & inside wrist of clinical trial patient before starting treatment with ZORYVE
Hand & inside wrist of clinical trial patient 1 week after ZORYVE treatment
Hand & inside wrist of clinical trial patient 4 weeks after ZORYVE treatment

Hand

11-YEAR-OLD

Day 0
Hand of clinical trial patient before starting treatment with ZORYVE
Hand of clinical trial patient 1 week after ZORYVE treatment
Hand of clinical trial patient 4 weeks after ZORYVE treatment

Chest

17-YEAR-OLD

Day 0
Chest of clinical trial patient before starting treatment with ZORYVE
Chest of clinical trial patient 1 week after ZORYVE treatment
Chest of clinical trial patient 4 weeks after ZORYVE treatment